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2023 PRIM&R Annual Conference

IACUC Protocol Review

Education, Qualifications, and Training

A17 - [IN-PERSON ONLY] Nonhuman Animal Welfare Toolbox for Protocol Review

Monday, December 4, 2023
1:00 PM – 2:00 PM ET
Location: Room 159 AB
IACUC/Animal Care and Use Learning Lab Series CPIA Accredited
This session is being held in-person only at PRIMR23. It will not be recorded for on-demand access or for the PRIMR23/SBER23 Virtual Meeting.

What are the basic knowledge and skills IACUC members need to effectively conduct protocol review? This session will discuss how to meet regulatory requirements, promote sound science, and ensure humane nonhuman animal care and use by discussing essential but challenging components of protocol review. Speakers and attendees will learn and share ways to efficiently assess nonhuman animal welfare aspects of protocols that are difficult to assess and may overlap with scientific review.

Learning Objectives:

  • Evaluate justifications for nonhuman animal use, including the chosen species, model justification, nonhuman animal numbers, and sex of the nonhuman animals
  • Discuss evaluation of experimental design through the lens of nonhuman animal welfare and care, particularly the components of experimental design in relation to study aims and nonhuman animal numbers
  • Determine if pain and distress is minimized, if alternatives have been adequately considered
  • Explore common risk-benefit paradigms and synthesis session components into a comprehensive risk-benefit analysis that focuses on the ethics of the proposed activity by weighing the potential benefits, the soundness of the proposed study design, and potential costs to the animals